HEMATO POLYVALENT SNAKE ANTIVENIN

Brand Name & Strength

Polyvalent Snake Antivenin 1 ml which contains: Russell’s Viper Venom (0.6mg), Green Pit Viper Venom (0.7mg), Malayan Pit Viper Venom (1.6mg)

Reconstitution

Reconstitute with 10 ml of WFI

Further Dilution

Dilute the reconstituted antivenom with 5 – 10 ml/kg diluent for children or 250 – 500 ml diluent for adult

Diluent

NS, D5

Administration & Infusion rate

IV infusion

Initial dose is 30 ml (3 vials)

Administer at 1 – 2 ml/min over 10 – 15 min. If no reaction, complete the infusion at a rate of 5 – 10 ml/min within less than 1 hr. If active bleeding still persist, the second dose can be administered after 2 hr or earlier.

Subsequent dose can be given every 6 hr according to clinical signs and symptoms.

Storage & Stability

RT

(<25 oC)

Fridge

(2 – 8 oC)

After Reconstitution

Use immediately -

After dilution

Use immediately -

Remarks

Gently swirl until serum become clear colourless or pale yellow liquid

Observe for any anaphylaxis and delay serum sickness reactions.

Skin test should be performed prior administration to avoid serious allergic reaction.